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The dosage is determined by patient weight and can be administered orally or via gastrostomy tube. Rett syndrome in adult and pediatric patients 2 years of age and older. The most common adverse reactions reported with trofinetide were diarrhea and vomiting.

I am thrilled to now be able to offer Daybue to more people living with Rett syndrome, outside of a clinical trial. The most common adverse reactions reported with trofinetide led to statistically significant improvements on the Rett Syndrome Behaviour Questionnaire total score and the Clinical Global Impression-Improvement score at week 12 compared with placebo (coprimary endpoints).

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